The Single Best Strategy To Use For pkrrating
The interfacial residues are remarkably conserved among eIF2α kinases and mutagenesis implicates the BTB dimer in PKR function18. FRET measurements exhibit which the kinase domains dimerize when PKR binds to activating dsRNAs19. These observations assist a product in which activating RNA serves as being a scaffold to bind various PKR monomers, esc